The first story, "Like Minds" details the initial meeting between Walter Bishop and William Bell, and their early work on the Synaptic Transfer System.
The second story, "The Prisoner", centers around a man who wakes up in prison, but doesn't know how he got there. Is he an unintended consequence of an experiment gone wrong?
You can purchase Fringe #1 at your local comic book store for $2.99 (if they are not sold-out already!).